DIS3L antibody
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935106861
info@markelab.com
name
DIS3L antibody
category
Primary Antibodies
provider
FineTest
reference
FNab02395
tested applications
ELISA, WB
Description
Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements(AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | DIS3 mitotic control homolog-like (DIS3L) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 121 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q8TF46 |
| Gene ID | 115752 |
| Alias | DIS3-like exonuclease 1,DIS3L,DIS3L1,KIAA1955 |
| Background | Antibody anti-DIS3L |
| Status | RUO |
| Note | Mol. Weight 121 kDa |
Descripción
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