DYRK1B antibody
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935106861
info@markelab.com
name
DYRK1B antibody
category
Primary Antibodies
provider
FineTest
reference
FNab02592
tested applications
ELISA, WB
Description
Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments. Inhibits the SHH and WNT1 pathways, thereby enhancing adipogenesis. In addition, promotes expression of the gluconeogenic enzyme glucose-6-phosphatase(G6PC).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B (DYRK1B) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 57 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9Y463 |
| Gene ID | 9149 |
| Alias | Dual specificity tyrosine-phosphorylation-regulated kinase 1B,Minibrain-related kinase,Mirk protein kinase,DYRK1B,MIRK |
| Background | Antibody anti-DYRK1B |
| Status | RUO |
| Note | Mol. Weight 57 kDa |
Descripción
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