ELK4 antibody

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Description
Involved in both transcriptional activation and repression. Interaction with SIRT7 leads to recruitment and stabilization of SIRT7 at promoters, followed by deacetylation of histone H3 at 'Lys-18'(H3K18Ac) and subsequent transcription repression. Forms a ternary complex with the serum response factor(SRF). Requires DNA-bound SRF for ternary complex formation and makes extensive DNA contacts to the 5'side of SRF, but does not bind DNA autonomously.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ELK4, ETS-domain protein(SRF accessory protein 1) (ELK4) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 47kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P28324 |
| Gene ID | 2005 |
| Alias | ETS domain-containing protein Elk-4,Serum response factor accessory protein 1 (SAP-1, SRF accessory protein 1),ELK4,SAP1 |
| Background | Antibody anti-ELK4 |
| Status | RUO |
| Note | Mol. Weight 47 kDa |
Descripción
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