γ-H2AX antibody
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935106861
info@markelab.com
name
γ-H2AX antibody
category
Primary Antibodies
provider
FineTest
reference
FNab10441
tested applications
WB, IHC, IF
Description
H2A.X becomes phosphorylated on serine 139 (to form gamma-H2AFX or H2AX139ph) in response to DNA double strand breaks (DSBs) generated by exogenous genotoxic agents and by stalled replication forks, which promotes DNA repair and maintains genomic stability.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | A synthetic phosphorylated peptide around S139 of human H2AX (γ-H2AX) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:20-1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 17 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P16104 |
| Alias | Histone H2AX (H2a/x),Histone H2A.X,H2AX,H2AFX |
| Background | Antibody anti-γ-H2AX |
| Status | RUO |
| Note | Mol. Weight 17 kDa |
Descripción
Related Products
γ-H2AX antibody
H2A.X becomes phosphorylated on serine 139 (to form gamma-H2AFX or H2AX139ph) in response to DNA double strand breaks (DSBs) generated by exogenous genotoxic agents and by stalled replication forks, which promotes DNA repair and maintains genomic stability.
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