HJURP antibody
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935106861
info@markelab.com
name
HJURP antibody
category
Primary Antibodies
provider
FineTest
reference
FNab03892
tested applications
ELISA, WB
Description
Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Holliday junction recognition protein (HJURP) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 70kd,83-85kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q8NCD3 |
| Gene ID | 55355 |
| Alias | Holliday junction recognition protein,14-3-3-associated AKT substrate,Fetal liver-expressing gene 1 protein,Up-regulated in lung cancer 9,HJURP,FAKTS,FLEG1,URLC9 |
| Background | Antibody anti-HJURP |
| Status | RUO |
| Note | Mol. Weight 70 kDa, 83-85 kDa |
Descripción
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HJURP antibody
Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions.
Ver Producto