HMGCL antibody
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935106861
info@markelab.com
name
HMGCL antibody
category
Primary Antibodies
provider
FineTest
reference
FNab03928
tested applications
ELISA, WB, IHC
Description
The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (HMGCL) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 30 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P35914 |
| Gene ID | 3155 |
| Alias | Hydroxymethylglutaryl-CoA lyase, mitochondrial (HL, HMG-CoA lyase),3-hydroxy-3-methylglutarate-CoA lyase,HMGCL |
| Background | Antibody anti-HMGCL |
| Status | RUO |
| Note | Mol. Weight 30 kDa |
Descripción
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The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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