HOOK1 antibody

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Description
Required for spermatid differentiation. Probably involved in the positioning of the microtubules of the manchette and the flagellum in relation to the membrane skeleton(By similarity). Component of the FTS/Hook/FHIP complex(FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex(the HOPS complex).
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Product specifications
Category | Primary Antibodies |
Immunogen Target | hook homolog 1(Drosophila) (HOOK1) |
Host | Rabbit |
Reactivity | Human, Mouse |
Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 85 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IHC, IF, IP |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | Q9UJC3 |
Gene ID | 51361 |
Alias | Protein Hook homolog 1 (h-hook1, hHK1),HOOK1 |
Background | Antibody anti-HOOK1 |
Status | RUO |
Note | Mol. Weight 85 kDa |
Descripción
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HOOK1 antibody
Required for spermatid differentiation. Probably involved in the positioning of the microtubules of the manchette and the flagellum in relation to the membrane skeleton(By similarity). Component of the FTS/Hook/FHIP complex(FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex(the HOPS complex).
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Protein Hook Homolog 1 (HOOK1) Antibody
HOOK1 Antibody is a Rabbit Polyclonal antibody against HOOK1. This gene encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. The encoded protein localizes to discrete punctuate subcellular structures, and interacts with several members of the Rab GTPase family involved in endocytosis. It is thought to link endocytic membrane trafficking to the microtubule cytoskeleton. Several alternatively spliced transcript variants have been identified, but the full-length nature of some of these variants has not been determined.
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