HOOK1 antibody

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935106861
info@markelab.com
name
HOOK1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab03967
tested applications
ELISA, WB, IHC, IF, IP

Description

Required for spermatid differentiation. Probably involved in the positioning of the microtubules of the manchette and the flagellum in relation to the membrane skeleton(By similarity). Component of the FTS/Hook/FHIP complex(FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex(the HOPS complex).

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
hook homolog 1(Drosophila) (HOOK1)
Host
Rabbit
Reactivity
Human, Mouse
Recommended Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
85 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC, IF, IP
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q9UJC3
Gene ID
51361
Alias
Protein Hook homolog 1 (h-hook1, hHK1),HOOK1
Background
Antibody anti-HOOK1
Status
RUO
Note
Mol. Weight 85 kDa

Descripción

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Required for spermatid differentiation. Probably involved in the positioning of the microtubules of the manchette and the flagellum in relation to the membrane skeleton(By similarity). Component of the FTS/Hook/FHIP complex(FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex(the HOPS complex).

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Protein Hook Homolog 1 (HOOK1) Antibody

HOOK1 Antibody is a Rabbit Polyclonal antibody against HOOK1. This gene encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. The encoded protein localizes to discrete punctuate subcellular structures, and interacts with several members of the Rab GTPase family involved in endocytosis. It is thought to link endocytic membrane trafficking to the microtubule cytoskeleton. Several alternatively spliced transcript variants have been identified, but the full-length nature of some of these variants has not been determined.

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