HOPX antibody
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935106861
info@markelab.com
name
HOPX antibody
category
Primary Antibodies
provider
FineTest
reference
FNab03970
tested applications
ELISA, IF, WB
Description
Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase(HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy(By similarity). May act as a tumor suppressor.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | HOP homeobox (HOPX) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IF: 1:50-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 8-12kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IF, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9BPY8 |
| Gene ID | 84525 |
| Alias | Homeodomain-only protein,Lung cancer-associated Y protein,Not expressed in choriocarcinoma protein 1,Odd homeobox protein 1,HOPX,HOD,HOP,LAGY,NECC1,OB1 |
| Background | Antibody anti-HOPX |
| Status | RUO |
| Note | Mol. Weight 8-12 kDa |
Descripción
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HOPX antibody
Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase(HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy(By similarity). May act as a tumor suppressor.
Ver Producto