IGHMBP2 antibody

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Description
5' to 3' helicase that unwinds RNA and DNA duplices in an ATP-dependent reaction. Acts as a transcription regulator. Required for the transcriptional activation of the flounder liver-type antifreeze protein gene. Exhibits strong binding specificity to the enhancer element B of the flounder antifreeze protein gene intron. Binds to the insulin II gene RIPE3B enhancer region. May be involved in translation(By similarity). DNA-binding protein specific to 5'-phosphorylated single-stranded guanine-rich sequence related to the immunoglobulin mu chain switch region. Preferentially binds to the 5'-GGGCT-3' motif. Interacts with tRNA-Tyr. Stimulates the transcription of the human neurotropic virus JCV.
Documents del producto
Product specifications
| Category | Primary Antibodies | 
| Immunogen Target | immunoglobulin mu binding protein 2 (IGHMBP2) | 
| Host | Rabbit | 
| Reactivity | Human | 
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 | 
| Clonality | polyclonal | 
| Conjugation | Unconjugated | 
| Isotype | IgG | 
| Observed MW | 109 kDa | 
| Purity | ≥95% as determined by SDS-PAGE | 
| Purification | Immunogen affinity purified | 
| Size 1 | 100µg | 
| Form | liquid | 
| Tested Applications | ELISA, WB, IHC | 
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | 
| UniProt ID | P38935 | 
| Gene ID | 3508 | 
| Alias | DNA-binding protein SMUBP-2,ATP-dependent helicase IGHMBP2,Glial factor 1 (GF-1),Immunoglobulin mu-binding protein 2,IGHMBP2,SMBP2,SMUBP2 | 
| Background | Antibody anti-IGHMBP2 | 
| Status | RUO | 
| Note | Mol. Weight 109 kDa | 
Descripción
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IGHMBP2 antibody
5' to 3' helicase that unwinds RNA and DNA duplices in an ATP-dependent reaction. Acts as a transcription regulator. Required for the transcriptional activation of the flounder liver-type antifreeze protein gene. Exhibits strong binding specificity to the enhancer element B of the flounder antifreeze protein gene intron. Binds to the insulin II gene RIPE3B enhancer region. May be involved in translation(By similarity). DNA-binding protein specific to 5'-phosphorylated single-stranded guanine-rich sequence related to the immunoglobulin mu chain switch region. Preferentially binds to the 5'-GGGCT-3' motif. Interacts with tRNA-Tyr. Stimulates the transcription of the human neurotropic virus JCV.
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