ITGA5 antibody

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935106861
info@markelab.com
name
ITGA5 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04347
tested applications
ELISA, WB
Description
Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site(site 2) which is distinct from the classical ligand-binding site(site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1(PubMed:18635536, PubMed:25398877). ITGA5:ITGB1 acts as a receptor for fibrillin-1(FBN1) and mediates R-G-D-dependent cell adhesion to FBN1(PubMed:12807887, PubMed:17158881).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | integrin, alpha 5 (ITGA5) |
| Host | Rabbit |
| Reactivity | Human, Rat, Mouse, Monkey |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 120 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P08648 |
| Alias | FNRA,CD49e,VLA-5,VLA5A,Integrin alpha-5,Integrin alpha-5,Fibronectin receptor subunit alpha,Integrin alpha-F |
| Background | Antibody anti-ITGA5 |
| Status | RUO |
| Note | Mol. Weight 120 kDa |
Descripción
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ITGA5 antibody
Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site(site 2) which is distinct from the classical ligand-binding site(site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1(PubMed:18635536, PubMed:25398877). ITGA5:ITGB1 acts as a receptor for fibrillin-1(FBN1) and mediates R-G-D-dependent cell adhesion to FBN1(PubMed:12807887, PubMed:17158881).
Ver Producto