ITM2C antibody
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Description
Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation(By similarity).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | integral membrane protein 2C (ITM2C) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 30 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9NQX7 |
| Gene ID | 81618 |
| Alias | Integral membrane protein 2C,Cerebral protein 14,Transmembrane protein BRI3,CT-BRI3,ITM2C,BRI3 |
| Background | Antibody anti-ITM2C |
| Status | RUO |
| Note | Mol. Weight 30 kDa |
Descripción
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