KHSRP antibody
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935106861
info@markelab.com
name
KHSRP antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04525
tested applications
ELISA, WB, IHC, IF
Description
Binds to the dendritic targeting element and may play a role in mRNA trafficking(By similarity). Part of a ternary complex that binds to the downstream control sequence(DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. May interact with single-stranded DNA from the far-upstream element(FUSE). May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements(AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | KH-type splicing regulatory protein (KHSRP) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 75 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q92945 |
| Gene ID | 8570 |
| Alias | Far upstream element-binding protein 2 (FUSE-binding protein 2),KH type-splicing regulatory protein (KSRP),p75,KHSRP,FUBP2 |
| Background | Antibody anti-KHSRP |
| Status | RUO |
| Note | Mol. Weight 75 kDa |
Descripción
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Human KHSRP (KH type-splicing regulatory protein) ELISA Kit
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KHSRP antibody
Binds to the dendritic targeting element and may play a role in mRNA trafficking(By similarity). Part of a ternary complex that binds to the downstream control sequence(DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. May interact with single-stranded DNA from the far-upstream element(FUSE). May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements(AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.
Ver Producto