LGI1 antibody
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935106861
info@markelab.com
name
LGI1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04760
tested applications
ELISA, WB, IHC
Description
Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors(By similarity). Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway. May play a role in the control of neuroblastoma cell survival.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | leucine-rich, glioma inactivated 1 (LGI1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:50-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 64 kDa, 58 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O95970 |
| Gene ID | 9211 |
| Alias | Leucine-rich glioma-inactivated protein 1,Epitempin-1,LGI1,EPT |
| Background | Antibody anti-LGI1 |
| Status | RUO |
| Note | Mol. Weight 64 kDa, 58 kDa |
Descripción
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