LZTS2 antibody
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Description
Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | leucine zipper, putative tumor suppressor 2 (LZTS2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 70-80 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9BRK4 |
| Gene ID | 84445 |
| Alias | Leucine zipper putative tumor suppressor 2 (hLZTS2),Protein LAPSER1,LZTS2,KIAA1813,LAPSER1 |
| Background | Antibody anti-LZTS2 |
| Status | RUO |
| Note | Mol. Weight 70-80 kDa |
Descripción
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