MED28 antibody
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Description
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May be part of a complex containing NF2/merlin that participates in cellular signaling to the actin cytoskeleton downstream of tyrosine kinase signaling pathways.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | mediator complex subunit 28 (MED28) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 25-28 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9H204 |
| Gene ID | 80306 |
| Alias | Mediator of RNA polymerase II transcription subunit 28,Endothelial-derived protein 1,Mediator complex subunit 28,Merlin and Grb2-interacting cytoskeletal protein (Magicin),Tumor angiogenesis marker EG-1,MED28,EG1 |
| Background | Antibody anti-MED28 |
| Status | RUO |
| Note | Mol. Weight 25-28 kDa |
Descripción
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