MGAT5B antibody

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Description
Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans. Catalyzes the transfer of N-acetylglucosamine(GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAcbeta1,2-Manalpha on both the alpha1,3-and alpha1,6-linked mannose arms in the core structure of N-glycan. Also acts on the GlcNAcbeta1,2-Manalpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adhesion and migration of neuronal cells via its activity in the O-mannosyl glycan pathway.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | mannosyl(alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B (MGAT5B) |
Host | Rabbit |
Reactivity | Human, Rat |
Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:2000 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 89-100 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IP |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | Q3V5L5 |
Gene ID | 146664 |
Alias | Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B,Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase B,GlcNAc-T Vb (GNT-Vb, hGnTVb),Mannoside acetylglucosaminyltransferase 5B,N-acetylglucosaminyl-transferase Vb,N-acetylglucosaminyltransferase IX (GNT-IX),MGAT5B,KIAA2008 |
Background | Antibody anti-MGAT5B |
Status | RUO |
Note | Mol. Weight 89-100 kDa |
Descripción
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