NEK3 antibody
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Description
Protein kinase which influences neuronal morphogenesis and polarity through effects on microtubules. Regulates microtubule acetylation in neurons. Contributes to prolactin-mediated phosphorylation of PXN and VAV2. Implicated in prolactin-mediated cytoskeletal reorganization and motility of breast cancer cells through mechanisms involving RAC1 activation and phosphorylation of PXN and VAV2.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | NIMA(never in mitosis gene a)-related kinase 3 (NEK3) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 52-60 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P51956 |
| Gene ID | 4752 |
| Alias | Serine/threonine-protein kinase Nek3,HSPK 36,Never in mitosis A-related kinase 3 (NimA-related protein kinase 3),NEK3 |
| Background | Antibody anti-NEK3 |
| Status | RUO |
| Note | Mol. Weight 52-60 kDa |
Descripción
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