NUDT21 antibody

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935106861
info@markelab.com
name
NUDT21 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05904
tested applications
ELISA, WB, IHC, IF, IP

Description

Component of the cleavage factor Im(CFIm) complex that plays a key role in pre-mRNA 3'-processing. Involved in association with CPSF6 or CPSF7 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. NUDT21/CPSF5 binds to cleavage and polyadenylation RNA substrates. The homodimer mediates simultaneous sequence-specific recognition of two 5'-UGUA-3' elements within the pre-mRNA. Binds to, but does not hydrolyze mono-and di-adenosine nucleotides. May have a role in mRNA export.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
nudix(nucleoside diphosphate linked moiety X)-type motif 21 (NUDT21)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
26 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC, IF, IP
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
O43809
Gene ID
11051
Alias
Cleavage and polyadenylation specificity factor subunit 5,Cleavage and polyadenylation specificity factor 25 kDa subunit (CPSF 25 kDa subunit),Cleavage factor Im complex 25 kDa subunit (CFIm25),Nucleoside diphosphate-linked moiety X motif 21 (Nudix motif 21),Nudix hydrolase 21,Pre-mRNA cleavage factor Im 68 kDa subunit,NUDT21,CFIM25,CPSF25,CPSF5
Background
Antibody anti-NUDT21
Status
RUO
Note
Mol. Weight 26 kDa

Descripción

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