NUDT21 antibody

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935106861
info@markelab.com
name
NUDT21 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05904
tested applications
ELISA, WB, IHC, IF, IP
Description
Component of the cleavage factor Im(CFIm) complex that plays a key role in pre-mRNA 3'-processing. Involved in association with CPSF6 or CPSF7 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. NUDT21/CPSF5 binds to cleavage and polyadenylation RNA substrates. The homodimer mediates simultaneous sequence-specific recognition of two 5'-UGUA-3' elements within the pre-mRNA. Binds to, but does not hydrolyze mono-and di-adenosine nucleotides. May have a role in mRNA export.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | nudix(nucleoside diphosphate linked moiety X)-type motif 21 (NUDT21) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 26 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IHC, IF, IP |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | O43809 |
Gene ID | 11051 |
Alias | Cleavage and polyadenylation specificity factor subunit 5,Cleavage and polyadenylation specificity factor 25 kDa subunit (CPSF 25 kDa subunit),Cleavage factor Im complex 25 kDa subunit (CFIm25),Nucleoside diphosphate-linked moiety X motif 21 (Nudix motif 21),Nudix hydrolase 21,Pre-mRNA cleavage factor Im 68 kDa subunit,NUDT21,CFIM25,CPSF25,CPSF5 |
Background | Antibody anti-NUDT21 |
Status | RUO |
Note | Mol. Weight 26 kDa |
Descripción
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Component of the cleavage factor Im(CFIm) complex that plays a key role in pre-mRNA 3'-processing. Involved in association with CPSF6 or CPSF7 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. NUDT21/CPSF5 binds to cleavage and polyadenylation RNA substrates. The homodimer mediates simultaneous sequence-specific recognition of two 5'-UGUA-3' elements within the pre-mRNA. Binds to, but does not hydrolyze mono-and di-adenosine nucleotides. May have a role in mRNA export.
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