SPP1 antibody
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935106861
info@markelab.com
name
SPP1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab06034
tested applications
ELISA, WB,IHC
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | secreted phosphoprotein 1 (SPP1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 66 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB,IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P10451 |
| Alias | Osteopontin,Bone sialoprotein 1,Nephropontin,Secreted phosphoprotein 1 (SPP-1),Urinary stone protein,Uropontin,SPP1,BNSP,OPN |
| Background | Antibody anti-SPP1 |
| Status | RUO |
| Note | Mol. Weight 66 kDa |
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SPP1 antibody
Osteopontin(OPN), also known as SPP1, is a secreted glycophosphoprotein that belongs to the small integrin-binding ligand N-linked glycoprotein(SIBLING) family. Originally isolated from bone, OPN has been found in kidney, vascular tissues, biological fluids, and various tumor tissues(PMID: 15138464; 16406521). OPN can interact with CD44 and integrins and regulate diverse biological processes. It has a multifaceted role in bone development and remodeling, and is also involved in the inflammatory and immune response, oncogenesis and cancer progression.
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