PAAF1 antibody
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Description
Inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency. Protects SUPT6H from proteasomal degradation.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | proteasomal ATPase-associated factor 1 (PAAF1) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 30 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9BRP4 |
| Gene ID | 80227 |
| Alias | Proteasomal ATPase-associated factor 1,Protein G-16,WD repeat-containing protein 71,PAAF1,WDR71 |
| Background | Antibody anti-PAAF1 |
| Status | RUO |
| Note | Mol. Weight 30 kDa |
Descripción
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