TENT4B antibody

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935106861
info@markelab.com
name
TENT4B antibody
category
Primary Antibodies
provider
FineTest
reference
FNab06139
tested applications
ELISA, WB, IP

Description

Catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Doesn't need a cofactor for polyadenylation activity(in vitro). Plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs. May play a role in sister chromatid cohesion.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
PAP associated domain containing 5 (TENT4B)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500 - 1:2000
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
50 kDa, 80 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IP
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q8NDF8
Gene ID
64282
Alias
Terminal nucleotidyltransferase 4B,Non-canonical poly(A) RNA polymerase PAPD5,PAP-associated domain-containing protein 5,Terminal guanylyltransferase,Terminal uridylyltransferase 3 (TUTase 3),Topoisomerase-related function protein 4-2 (TRF4-2),TENT4B,GLD4,PAPD5,TRF4-2,TUT3
Background
Antibody anti-TENT4B
Status
RUO
Note
Mol. Weight 50 kDa, 80 kDa

Descripción

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