PELI2 antibody

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935106861
info@markelab.com
name
PELI2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab06304
tested applications
ELISA, WB, IHC, IF
Description
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates IL1B-induced IRAK1 'Lys-63'-linked polyubiquitination and possibly 'Lys-48'-linked ubiquitination. May be important for LPS-and IL1B-induced MAP3K7-dependent, but not MAP3K3-dependent, NF-kappa-B activation. Can activate the MAP(mitogen activated protein) kinase pathway leading to activation of ELK1.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | pellino homolog 2(Drosophila) (PELI2) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 45-50 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IHC, IF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | Q9HAT8 |
Gene ID | 57161 |
Alias | E3 ubiquitin-protein ligase pellino homolog 2 (Pellino-2),RING-type E3 ubiquitin transferase pellino homolog 2,PELI2 |
Background | Antibody anti-PELI2 |
Status | RUO |
Note | Mol. Weight 45-50 kDa |
Descripción
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