PGA5 antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
This antibody can recognize PGA3, PGA4, PGA5.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | pepsinogen 5, group I(pepsinogen A) (PGA5) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 42 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P0DJD9 |
| Gene ID | 5222 |
| Alias | Pepsin A-5,Pepsinogen-5,PGA5 |
| Background | Antibody anti-PGA5 |
| Status | RUO |
| Note | Mol. Weight 42 kDa |
Descripción
Related Products
Pepsin A-5 (PGA5) Antibody
PGA5: Pepsinogen 5, group I (pepsinogen A).Pepsinogens are the inactive precursors of pepsin, the major acid protease found in the stomach.Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa.Pepsin consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus.Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity (pH 1-3) for pepsin function.Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids.Pepsin shows extremely broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent.PGA5 is a member of the subfamily A1 within the pepsin family and is the predominant endopeptidase in the gastric juice of vertebrates.PGA5 is inhibited by ovUS-1, a uterine serpin.
Ver Producto
Pepsin A-5 (PGA5) Antibody
PGA3 shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent.
Ver Producto