PFDN5 antibody
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Description
Binds specifically to cytosolic chaperonin(c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Represses the transcriptional activity of MYC.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | prefoldin subunit 5 (PFDN5) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 17 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q99471 |
| Gene ID | 5204 |
| Alias | Prefoldin subunit 5,Myc modulator 1,c-Myc-binding protein Mm-1,PFDN5,MM1,PFD5 |
| Background | Antibody anti-PFDN5 |
| Status | RUO |
| Note | Mol. Weight 17 kDa |
Descripción
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PFDN5 antibody
Binds specifically to cytosolic chaperonin(c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Represses the transcriptional activity of MYC.
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PFDN5 Antibody is a Rabbit Polyclonal antibody against PFDN5. This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described.
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