PLCD4 antibody
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Description
Hydrolyzes the phosphatidylinositol 4,5-bisphosphate(PIP2) to generate 2 second messenger molecules diacylglycerol(DAG) and inositol 1,4,5-trisphosphate(IP3). DAG mediates the activation of protein kinase C(PKC), while IP3 releases Ca(2+) from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca(2+) mobilization in the zona pellucida-induced acrosome reaction. May play a role in cell growth. Modulates the liver regeneration in cooperation with nuclear PKC. Overexpression up-regulates the Erk signaling pathway and proliferation.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | phospholipase C, delta 4 (PLCD4) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9BRC7 |
| Gene ID | 84812 |
| Alias | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (hPLCD4),Phosphoinositide phospholipase C-delta-4,Phospholipase C-delta-4 (PLC-delta-4),PLCD4 |
| Background | Antibody anti-PLCD4 |
| Status | RUO |
| Note | This product is for research use only. |
Descripción
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