PLEKHF1 antibody
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Description
May induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane(LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization(MMP) resulting in the release of PDCD8.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | pleckstrin homology domain containing, family F(with FYVE domain) member 1 (PLEKHF1) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 31 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q96S99 |
| Gene ID | 79156 |
| Alias | Pleckstrin homology domain-containing family F member 1 (PH domain-containing family F member 1),Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains (Apoptosis-inducing protein),PH and FYVE domain-containing protein 1,Phafin-1,Zinc finger FYVE domain-containing protein 15,PLEKHF1,APPD,LAPF,ZFYVE15 |
| Background | Antibody anti-PLEKHF1 |
| Status | RUO |
| Note | Mol. Weight 31 kDa |
Descripción
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