PPM1B antibody
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935106861
info@markelab.com
name
PPM1B antibody
category
Primary Antibodies
provider
FineTest
reference
FNab06685
tested applications
ELISA, WB, IHC
Description
Enzyme with a broad specificity. Dephosphorylates CDK2 and CDK6 in vitro. Dephosphorylates PRKAA1 and PRKAA2. Inhibits TBK1-mediated antiviral signaling by dephosphorylating it at 'Ser-172'. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | protein phosphatase 1B(formerly 2C), magnesium-dependent, beta isoform (PPM1B) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 50-53 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O75688 |
| Gene ID | 5495 |
| Alias | Protein phosphatase 1B,Protein phosphatase 2C isoform beta (PP2C-beta),PPM1B,PP2CB |
| Background | Antibody anti-PPM1B |
| Status | RUO |
| Note | Mol. Weight 50-53 kDa |
Descripción
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