RPL7 antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ribosomal protein L7 (RPL7) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:3000; IP: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:50-1:500 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 29-30 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IP, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P18124 |
| Gene ID | 6129 |
| Alias | Large ribosomal subunit protein uL30,60S ribosomal protein L7,RPL7 |
| Background | Antibody anti-RPL7 |
| Status | RUO |
| Note | Mol. Weight 29-30 kDa |
Descripción
Related Products
RPL7 antibody
Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs.
Ver Producto
Ribosomal Protein L7 (RPL7) Antibody
RPL7 Antibody is a Rabbit Polyclonal antibody against RPL7. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L30P family of ribosomal proteins. It contains an N-terminal basic region-leucine zipper (BZIP)-like domain and the RNP consensus submotif RNP2. In vitro the BZIP-like domain mediates homodimerization and stable binding to DNA and RNA, with a preference for 28S rRNA and mRNA. The protein can inhibit cell-free translation of mRNAs, suggesting that it plays a regulatory role in the translation apparatus. It is located in the cytoplasm. The protein has been shown to be an autoantigen in patients with systemic autoimmune diseases, such as systemic lupus erythematosus. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Ver Producto
Ribosomal Protein L7 (RPL7) Antibody
Rabbit polyclonal antibody against RPL7 protein. Immunogen region is C-terminal.
Ver Producto