SEC14L1 antibody
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935106861
info@markelab.com
name
SEC14L1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07678
tested applications
ELISA, WB
Description
May play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of DDX58/RIG-I, the cytoplasmic sensor of viral nucleic acids. Prevents the interaction of DDX58 with MAVS/IPS1, an important step in signal propagation(PubMed:23843640). May also regulate the SLC18A3 and SLC5A7 cholinergic transporters(PubMed:17092608).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | SEC14-like 1 (SEC14L1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 81 kDa, 77 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q92503 |
| Gene ID | 6397 |
| Alias | SEC14-like protein 1,SEC14L1,SEC14L |
| Background | Antibody anti-SEC14L1 |
| Status | RUO |
| Note | Mol. Weight 81 kDa, 77 kDa |
Descripción
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