SIKE1 antibody
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935106861
info@markelab.com
name
SIKE1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07867
tested applications
ELISA, WB, IHC
Description
Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus-and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements(ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | suppressor of IKK epsilon (SIKE1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 24 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9BRV8 |
| Gene ID | 80143 |
| Alias | Suppressor of IKBKE 1,Suppressor of IKK-epsilon,SIKE1,SIKE |
| Background | Antibody anti-SIKE1 |
| Status | RUO |
| Note | Mol. Weight 24 kDa |
Descripción
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