SLC25A33 antibody
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Description
Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria(PubMed:25320081). Transports preferentially uracil, thymine, and cytosine(deoxy)nucleoside di-and triphosphates by an antiport mechanism(PubMed:25320081). Also transports guanine but not adenine(deoxy)nucleotides(PubMed:25320081). Is inhibited strongly by pyridoxal 5'-phosphate, 4,7-diphenyl-1,10-phenanthroline, tannic acid, and mercurials(mercury dichloride, mersalyl acid, p-hydroxymercuribenzoate)(PubMed:25320081). Participates in mitochondrial genome maintenance, regulation of mitochondrial membrane potential and mitochondrial respiration(PubMed:20453889). Upon INS or IGF1 stimulation regulates cell growth and proliferation by controlling mitochondrial DNA replication and transcription, the ratio of mitochondria-to nuclear-encoded components of the electron transport chain resulting in control of mitochondrial ROS production(PubMed:20453889, PubMed:17596519). Participates in dendritic cell endocytosis and may associate with mitochondrial oxidative phosphorylation(PubMed:14715278).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | solute carrier family 25, member 33 (SLC25A33) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 35-40 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9BSK2 |
| Gene ID | 84275 |
| Alias | Solute carrier family 25 member 33,Bone marrow stromal cell mitochondrial carrier protein (BMSC-MCP, HuBMSC-MCP),Protein PNC1,SLC25A33 |
| Background | Antibody anti-SLC25A33 |
| Status | RUO |
| Note | Mol. Weight 35-40 kDa |
Descripción
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SLC25A33 antibody
Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria(PubMed:25320081). Transports preferentially uracil, thymine, and cytosine(deoxy)nucleoside di-and triphosphates by an antiport mechanism(PubMed:25320081). Also transports guanine but not adenine(deoxy)nucleotides(PubMed:25320081). Is inhibited strongly by pyridoxal 5'-phosphate, 4,7-diphenyl-1,10-phenanthroline, tannic acid, and mercurials(mercury dichloride, mersalyl acid, p-hydroxymercuribenzoate)(PubMed:25320081). Participates in mitochondrial genome maintenance, regulation of mitochondrial membrane potential and mitochondrial respiration(PubMed:20453889). Upon INS or IGF1 stimulation regulates cell growth and proliferation by controlling mitochondrial DNA replication and transcription, the ratio of mitochondria-to nuclear-encoded components of the electron transport chain resulting in control of mitochondrial ROS production(PubMed:20453889, PubMed:17596519). Participates in dendritic cell endocytosis and may associate with mitochondrial oxidative phosphorylation(PubMed:14715278).
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