LCP2 antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Involved in T-cell antigen receptor mediated signaling.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | lymphocyte cytosolic protein 2(SH2 domain containing leukocyte protein of 76kDa) (LCP2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:50-1:500 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 70kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB,IHC,IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q13094 |
| Alias | Lymphocyte cytosolic protein 2,SH2 domain-containing leukocyte protein of 76 kDa,SLP-76 tyrosine phosphoprotein (SLP76),LCP2 |
| Background | Antibody anti-LCP2 |
| Status | RUO |
| Note | Mol. Weight 70 kDa |
Descripción
Related Products
Lymphocyte Cytosolic Protein 2 (LCP2) Antibody
LCP2 Antibody is a Rabbit Polyclonal antibody against LCP2. SLP-76 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP-76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2-terminus contains an acidic region that includes a PEST domain and several tyrosine residues which are phosphorylated following TCR ligation. SLP-76 also contains a central proline-rich domain and a COOH-terminal SH2 domain. A number of additional proteins have been identified that associate with SLP-76 both constitutively and inducibly following receptor ligation, supporting the notion that SLP-76 functions as an adaptor or scaffold protein. Studies using SLP-76 deficient T cell lines or mice have provided strong evidence that SLP-76 plays a positive role in promoting T cell development and activation as well as mast cell and platelet function.
Ver Producto
Mouse Lymphocyte Cytosolic Protein 2 (LCP2) Protein
Mouse Lymphocyte Cytosolic Protein 2 (LCP2) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Ver Producto