SMG5 antibody
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
SMG5 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab08025
tested applications
ELISA, WB
Description
Plays a role in nonsense-mediated mRNA decay. Does not have RNase activity by itself. Promotes dephosphorylation of UPF1. Together with SMG7 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A(PP2A), thereby triggering UPF1 dephosphorylation. Necessary for TERT activity.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Smg-5 homolog, nonsense mediated mRNA decay factor (SMG5) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 114 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9UPR3 |
| Gene ID | 23381 |
| Alias | Nonsense-mediated mRNA decay factor SMG5,EST1-like protein B,LPTS-RP1,LPTS-interacting protein,SMG-5 homolog (hSMG-5),SMG5,EST1B,KIAA1089 |
| Background | Antibody anti-SMG5 |
| Status | RUO |
| Note | Mol. Weight 114 kDa |
Descripción
Related Products
SMG5 antibody
Plays a role in nonsense-mediated mRNA decay. Does not have RNase activity by itself. Promotes dephosphorylation of UPF1. Together with SMG7 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A(PP2A), thereby triggering UPF1 dephosphorylation. Necessary for TERT activity.
Ver Producto
SMG5, Nonsense Mediated mRNA Decay Factor (SMG5) Antibody
SMG5 is involved in nonsense-mediated mRNA decay (Ohnishi et al., 2003 [PubMed 14636577]).
Ver Producto
SMG5, Nonsense Mediated mRNA Decay Factor (SMG5) Antibody
SMG5 Antibody is a Rabbit Polyclonal against SMG5.
Ver Producto