SYTL2 antibody
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935106861
info@markelab.com
name
SYTL2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab08460
tested applications
ELISA, WB, IHC
Description
Isoform 1 acts as a RAB27A effector protein and plays a role in cytotoxic granule exocytosis in lymphocytes. It is required for cytotoxic granule docking at the immunologic synapse. Isoform 4 binds phosphatidylserine(PS) and phosphatidylinositol-4,5-bisphosphate(PIP2) and promotes the recruitment of glucagon-containing granules to the cell membrane in pancreatic alpha cells. Binding to PS is inhibited by Ca(2+) while binding to PIP2 is Ca(2+) insensitive.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | synaptotagmin-like 2 (SYTL2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 100-105 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9HCH5 |
| Gene ID | 54843 |
| Alias | Synaptotagmin-like protein 2,Breast cancer-associated antigen SGA-72M,Exophilin-4,SYTL2,KIAA1597,SGA72M,SLP2,SLP2A |
| Background | Antibody anti-SYTL2 |
| Status | RUO |
| Note | Mol. Weight 100-105 kDa |
Descripción
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