TIA1 antibody

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935106861
info@markelab.com
name
TIA1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab08685
tested applications
ELISA, WB, IHC, IF

Description

The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
TIA1 cytotoxic granule-associated RNA binding protein (TIA1)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:20 - 1:100
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
54 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC, IF
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
UniProt ID
P31483
Gene ID
7072
Alias
Cytotoxic granule associated RNA binding protein TIA1,Nucleolysin TIA-1 isoform p40,RNA-binding protein TIA-1,T-cell-restricted intracellular antigen-1 (TIA-1),p40-TIA-1,TIA1
Background
Antibody anti-TIA1
Status
RUO
Note
Mol. Weight 54 kDa

Descripción

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