VPS25 antibody
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935106861
info@markelab.com
name
VPS25 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab09431
tested applications
ELISA, WB, IHC
Description
Component of the ESCRT-II complex(endosomal sorting complex required for transport II), which is required for multivesicular body(MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. The ESCRT-II complex may be involved in facilitating the budding of certain RNA viruses.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | vacuolar protein sorting 25 homolog (VPS25) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 21 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9BRG1 |
| Gene ID | 84313 |
| Alias | Vacuolar protein-sorting-associated protein 25 (hVps25),Dermal papilla-derived protein 9,ELL-associated protein of 20 kDa,ESCRT-II complex subunit VPS25,VPS25,DERP9,EAP20 |
| Background | Antibody anti-VPS25 |
| Status | RUO |
| Note | Mol. Weight 21 kDa |
Descripción
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VPS25 antibody
Component of the ESCRT-II complex(endosomal sorting complex required for transport II), which is required for multivesicular body(MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. The ESCRT-II complex may be involved in facilitating the budding of certain RNA viruses.
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