WAPL antibody
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935106861
info@markelab.com
name
WAPL antibody
category
Primary Antibodies
provider
FineTest
reference
FNab09467
tested applications
ELISA, WB
Description
The wings apart-like(WAPL, or WAPAL) protein was originally identified as a gene product that potentially regulates heterochromatin organization in Drosophila melanogaster. Human WAPL is a cohesin-binding protein that promotes sister-chromatid resolution in mitotic prophase. Overexpression of WAPL disturbs mitosis and cytokinesis, and contributes to tumor progression by induction of chromosomal instability.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | wings apart-like homolog(Drosophila) (WAPL) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:5000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 140 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q7Z5K2 |
| Alias | Wings apart-like protein homolog,Friend of EBNA2 protein,WAPL cohesin release factor,WAPL,FOE,KIAA0261,WAPAL |
| Background | Antibody anti-WAPL |
| Status | RUO |
| Note | Mol. Weight 140 kDa |
Descripción
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The wings apart-like(WAPL, or WAPAL) protein was originally identified as a gene product that potentially regulates heterochromatin organization in Drosophila melanogaster. Human WAPL is a cohesin-binding protein that promotes sister-chromatid resolution in mitotic prophase. Overexpression of WAPL disturbs mitosis and cytokinesis, and contributes to tumor progression by induction of chromosomal instability.
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