MAP3K20 antibody
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Description
This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | sterile alpha motif and leucine zipper containing kinase AZK (MAP3K20) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:20 - 1:50 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 55 kDa, 100 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9NYL2 |
| Gene ID | 51776 |
| Alias | Mitogen-activated protein kinase kinase kinase 20,Human cervical cancer suppressor gene 4 protein (HCCS-4),Leucine zipper- and sterile alpha motif-containing kinase,MLK-like mitogen-activated protein triple kinase,Mitogen-activated protein kinase kinase kinase MLT,Mixed lineage kinase 7,Mixed lineage kinase-related kinase (MLK-related kinase, MRK),Sterile alpha motif- and leucine zipper-containing kinase AZK,MAP3K20,MLK7,MLTK,ZAK |
| Background | Antibody anti-MAP3K20 |
| Status | RUO |
| Note | Mol. Weight 55 kDa, 100 kDa |
Descripción
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