ZC3H8 antibody
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935106861
info@markelab.com
name
ZC3H8 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab09605
tested applications
ELISA, WB
Description
Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region(IRR) of the GATA3 gene(By similarity). Component of the little elongation complex(LEC), a complex required to regulate small nuclear RNA(snRNA) gene transcription by RNA polymerase II and III(PubMed:23932780). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | zinc finger CCCH-type containing 8 (ZC3H8) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:1000-1:10000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 34 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q8N5P1 |
| Gene ID | 84524 |
| Alias | Zinc finger CCCH domain-containing protein 8,ZC3H8,ZC3HDC8 |
| Background | Antibody anti-ZC3H8 |
| Status | RUO |
| Note | Mol. Weight 34 kDa |
Descripción
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