ZWILCH antibody
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935106861
info@markelab.com
name
ZWILCH antibody
category
Primary Antibodies
provider
FineTest
reference
FNab09761
tested applications
ELISA, WB, IHC
Description
Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex(PubMed:15824131).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Zwilch, kinetochore associated, homolog(Drosophila) (ZWILCH) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:200-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 67 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9H900 |
| Gene ID | 55055 |
| Alias | Protein zwilch homolog (hZwilch),ZWILCH |
| Background | Antibody anti-ZWILCH |
| Status | RUO |
| Note | Mol. Weight 67 kDa |
Descripción
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ZWILCH antibody
Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex(PubMed:15824131).
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