ATR-Interacting Protein (ATRIP) Antibody
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Description
ATRIP Antibody is a Rabbit Polyclonal antibody against ATRIP. This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ATR-Interacting Protein (ATRIP) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200, IP: 0.5 µg - 4 µg antibody per 200 µg - 400 µg extracts of whole cells. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC, IP |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8WXE1 |
| Gene ID | 84126 |
| NCBI Accession | NP_569055.1 |
| Background | Antibody anti-ATRIP |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
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ATRIP antibody
Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein.
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ATR-Interacting Protein (ATRIP) Antibody
ATRIP Antibody is a Rabbit Polyclonal antibody against ATRIP. This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.
Ver Producto
ATR-Interacting Protein (ATRIP) Antibody
ATRIP Antibody is a Rabbit Polyclonal antibody against ATRIP. This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.
Ver Producto