Basic Leucine Zipper Transcription Factor, ATF-Like 2 (BATF2) Antibody
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Description
BATF2 Antibody is a Rabbit Polyclonal against BATF2.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Basic Leucine Zipper Transcription Factor, ATF-Like 2 (BATF2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/200 - 1/1000, IP: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, IP |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8N1L9 |
| Gene ID | 116071 |
| OMIM | 614983 |
| Alias | B-ATF-2 |
| Background | Antibody anti-BATF2 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
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AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Following infection, participates in the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes(By similarity). Selectively suppresses CYR61/CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CYR61 and inhibits CYR61-induced anchorage-independent growth and invasion in several cancer types, such as breast cancer, malignant glioma and metastatic melanoma. Possibly acts by interfering with AP-1 binding to CYR61 promoter.
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Basic Leucine Zipper Transcription Factor, ATF-Like 2 (BATF2) Antibody
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Basic Leucine Zipper Transcription Factor, ATF-Like 2 (BATF2) Antibody
BATF2 Antibody is a Rabbit Polyclonal against BATF2.
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