Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) Antibody
286€ (100 µl)
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935106861
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name
Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx175624
tested applications
WB, IHC, IF/ICC
Description
Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) Antibody is a Rabbit Polyclonal antibody against Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) Immunogen: abx652708 - Recombinant BAI1 (Ala31-Pro350) expressed in E. coli |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | ADGRB1,BAI1,GDAIF |
| Background | Antibody anti-ADGRB1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
ADGRB1, also known as BAI1 (Brain-Specific Angiogenesis Inhibitor 1), is a member of the adhesion G protein-coupled receptor (GPCR) family predominantly expressed in the brain. It plays a critical role in inhibiting angiogenesis, promoting synaptic plasticity, and mediating phagocytic clearance of apoptotic cells and pathogens. Structurally, ADGRB1 contains multiple extracellular domains that facilitate interactions with matrix proteins and apoptotic cell markers. Dysregulation of ADGRB1 is associated with glioblastoma, as it suppresses tumor angiogenesis and growth, and its loss can contribute to tumor progression. Additionally, it has been implicated in synaptic function and neuronal health, with potential roles in neurodevelopmental disorders and neurodegeneration. ADGRB1’s ability to link extracellular signals to intracellular pathways highlights its importance in vascular regulation and brain function.
Related Products
Human Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) Protein
Human Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) Protein is a recombinant Human protein expressed in E. coli.
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