Cone-Rod Homeobox (CRX) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
CRX Antibody is a Rabbit Polyclonal antibody against CRX. The protein encoded by this gene is a photoreceptor-specific transcription factor which plays a role in the differentiation of photoreceptor cells. This homeodomain protein is necessary for the maintenance of normal cone and rod function. Mutations in this gene are associated with photoreceptor degeneration, Leber congenital amaurosis type III and the autosomal dominant cone-rod dystrophy 2. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Cone-Rod Homeobox (CRX) |
| Host | Rabbit |
| Reactivity | Mouse |
| Recommended Dilution | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB, IF/ICC |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O43186 |
| Gene ID | 1406 |
| NCBI Accession | NP_000545.1 |
| OMIM | 120970 |
| Background | Antibody anti-CRX |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
Related Products
CRX antibody
Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors.
Ver Producto
Cone-Rod Homeobox (CRX) Antibody
CRX Antibody is a Rabbit Polyclonal antibody against CRX. The protein encoded by this gene is a photoreceptor-specific transcription factor which plays a role in the differentiation of photoreceptor cells. This homeodomain protein is necessary for the maintenance of normal cone and rod function. Mutations in this gene are associated with photoreceptor degeneration, Leber congenital amaurosis type III and the autosomal dominant cone-rod dystrophy 2. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.
Ver Producto
Cone-Rod Homeobox (CRX) Antibody
Cone-Rod Homeobox Antibody is a Rabbit Polyclonal antibody against Cone-Rod Homeobox.
Ver Producto