COP9 Signalosome Subunit 4 (COPS4) Antibody
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Description
Cop9 Constitutive Photomorphogenic Homolog Subunit 4 (Arabidopsis) Antibody is a Rabbit Polyclonal antibody against Cop9 Constitutive Photomorphogenic Homolog Subunit 4 (Arabidopsis).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | COP9 Signalosome Subunit 4 (COPS4) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9BT78 |
| Gene ID | 51138 |
| NCBI Accession | NP_001244935.1, NM_001258006.1, NP_001317656.1, NM_001330727.1, NP_057213.2, NM_016129.2 |
| OMIM | 616008 |
| Background | Antibody anti-COPS4 |
| Status | RUO |
Descripción
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COPS4 antibody
Component of the COP9 signalosome complex(CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin(Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. Also involved in the deneddylation of non-cullin subunits such as STON2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1, IRF8/ICSBP and SNAPIN, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
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COP9 Signalosome Subunit 4 (COPS4) Antibody
Cop9 Constitutive Photomorphogenic Homolog Subunit 4 (Arabidopsis) Antibody is a Rabbit Polyclonal antibody against Cop9 Constitutive Photomorphogenic Homolog Subunit 4 (Arabidopsis).
Ver ProductoCOP9 Signalosome Subunit 4 (COPS4) Antibody
COPS4 Antibody is a Rabbit Polyclonal against COPS4.
Ver Producto