Coronin 1B (CORO1B) Antibody
357.5€ (100 µg)
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name
Coronin 1B (CORO1B) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx145389
tested applications
ELISA, WB, IHC
Description
CORO1B Antibody is a Rabbit Polyclonal against CORO1B.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Coronin 1B (CORO1B) Immunogen: Recombinant fragment corresponding to 34-287 AA of human CORO1B. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 54 kDa |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | BC006449 |
| Alias | p57,IMD8,TACO,CLABP,HCORO1,CLIPINA,CORO1,Tryptophan aspartate-containing coat protein (TACO),Coronin-like protein p57,Coronin-like protein A,Clipin-A,Coronin-1A |
| Background | Antibody anti-CORO1B |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Coronin 1B (CORO1B) is another member of the coronin family, sharing functional similarities with other coronin proteins but also exhibiting unique features in different tissues. CORO1B is involved in regulating the dynamics of actin filaments within cells, particularly in the context of immune cells and neurons. It plays a key role in cellular processes such as migration, endocytosis, and phagocytosis, especially in macrophages. The protein also contributes to the stability of actin networks in immune responses, which is essential for effective immune surveillance and pathogen elimination. Additionally, CORO1B has been implicated in the regulation of synaptic function in neurons. Its dysregulation has been associated with disorders related to the immune system and neurodegeneration, emphasizing its importance in both immune function and neuronal activity.
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Coronin 1B (CORO1B) Antibody
Members of the coronin family, such as CORO1B, are WD repeat-containing actin-binding proteins that regulate cell motility (Cai et al., 2005 [PubMed 16027158]).
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