Coronin 2B (CORO2B) Antibody
292.5€ (80 µl)
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935106861
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name
Coronin 2B (CORO2B) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx030151
tested applications
ELISA, WB
Description
CORO2B may play a role in the reorganization of neuronal actin structure.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Coronin 2B (CORO2B) Immunogen: KLH-conjugated synthetic peptide between 1-27 amino acids from the N-terminal region of human CORO2B. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 55 kDa |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9UQ03 |
| Alias | IR10,WDR2,CLIPINB,WD repeat-containing protein 2,Coronin-2A |
| Background | Antibody anti-CORO2B |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Coronin 2B (CORO2B) is another member of the coronin protein family, and it shares similarities with CORO2A in its role of regulating actin dynamics. CORO2B is particularly important in the context of immune cells, such as macrophages, where it helps in processes like phagocytosis, cell migration, and the maintenance of actin cytoskeleton integrity. It also contributes to the regulation of immune responses and is involved in signaling pathways that control the activity of immune cells. In addition to its role in immune function, CORO2B has also been found to influence cell signaling in other tissues, including neurons, where it impacts processes related to cell movement and plasticity. Dysregulation of CORO2B can lead to immune deficiencies and other pathologies related to actin regulation.
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