Coronin 6 (CORO6) Antibody

Este producto es parte de CORO - Coronin
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292.5€ (80 µl)

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935106861
info@markelab.com
name
Coronin 6 (CORO6) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx032318
tested applications
ELISA, WB, IHC

Description

CORO6 Antibody is a Rabbit Polyclonal antibody against CORO6.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Target: Coronin 6 (CORO6)
Immunogen: KLH-conjugated synthetic peptide between 337-365 amino acids from the C-terminal region of human CORO6.
Host
Rabbit
Reactivity
Human, Mouse
Recommended Dilution
WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
Calculated MW: 52.8 kDa
Purification
Purified through a protein A column, followed by peptide affinity purification.
Size 1
80 µl
Size 2
400 µl
Form
Liquid
Tested Applications
ELISA, WB, IHC
Buffer
PBS containing 0.09% sodium azide.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q6QEF8
Alias
ClipinE, Coronin-like protein E,Coronin-6
Background
Antibody anti-CORO6
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

Coronin 6 (CORO6) is another member of the coronin family, but it has a more specialized function compared to other coronin proteins. CORO6 has been shown to be involved in the regulation of intracellular signaling and the movement of vesicles within cells. It contributes to the proper functioning of the cytoskeleton and is involved in the trafficking and signaling mechanisms that control cellular processes like cell migration, differentiation, and adhesion. Like the other coronins, CORO6 is essential for immune function and neuronal activities, and it has been implicated in maintaining the structure of immune synapses and in neuronal development. Alterations in CORO6 activity can potentially affect both immune responses and neural network formation, leading to disorders related to cell signaling and movement.

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