Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Antibody
299€ (100 µg)
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935106861
info@markelab.com
name
Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx019089
tested applications
WB, IF/ICC, IP
Description
GAPDH Antibody is a Mouse Monoclonal antibody against Human, Mouse, Rat, Dog, Rabbit, Pig and Chicken.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Immunogen: Recombinant Human GAPDH protein. |
| Host | Mouse |
| Reactivity | Human, Mouse, Rat, Dog, Rabbit, Pig, Chicken |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | WB: 1/10000-1/200000, IF/ICC: 1/200-1/500, IP: 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Size 1 | 100 µg |
| Tested Applications | WB, IF/ICC, IP |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | GAPDH, GAPD, G3PD, HEL-S-162eP,Peptidyl-cysteine S-nitrosylase GAPDH |
| Background | Antibody anti-GAPDH |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a multifunctional enzyme predominantly involved in glycolysis, catalyzing the oxidative phosphorylation of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate using NAD+ as a cofactor. Beyond its metabolic role, GAPDH participates in various non-metabolic processes, including transcriptional regulation, DNA repair, and cell apoptosis. Its involvement in oxidative stress response and as a target for S-nitrosylation connects it to neurodegenerative diseases such as Alzheimer's and Parkinson's. Furthermore, GAPDH can translocate to the nucleus under stress conditions, influencing apoptotic pathways.
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