Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Antibody

Este producto es parte de GAPDH - Glyceraldehyde-3-phosphate dehydrogenase
Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Antibody
1040€ (1 mg)

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Name
Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx021094
Tested Applications
ELISA, WB, IF/ICC

Description

GAPDH Antibody is a Mouse monoclonal antibody against GAPDH.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
Target: Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH)
Immunogen: Human GAPDH
Host
Mouse
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Monoclonal
Conjugation
Unconjugated
Isotype
IgG1
Purification
Purified from Mouse cell culture by Protein A Chromatography.
Size 1
1 mg
Form
Liquid
Tested Applications
ELISA, WB, IF/ICC
Buffer
Buffer contains NaN3 as a preservative.
Availability
Shipped within 10-20 working days.
Storage
Aliquot and store at 2°C to 8°C upon receipt.
Dry Ice
No
Alias
GAPDH, GAPD, G3PD, HEL-S-162eP,Peptidyl-cysteine S-nitrosylase GAPDH
Background
Antibody anti-GAPDH
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Background

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a multifunctional enzyme predominantly involved in glycolysis, catalyzing the oxidative phosphorylation of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate using NAD+ as a cofactor. Beyond its metabolic role, GAPDH participates in various non-metabolic processes, including transcriptional regulation, DNA repair, and cell apoptosis. Its involvement in oxidative stress response and as a target for S-nitrosylation connects it to neurodegenerative diseases such as Alzheimer's and Parkinson's. Furthermore, GAPDH can translocate to the nucleus under stress conditions, influencing apoptotic pathways.

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